How Genetics Influences Your Eye Health: An Ophthalmologist’s Perspective

How Genetics Influences Your Eye Health: An Ophthalmologist’s Perspective

Our genes shape us. They determine not only our physical attributes but also our susceptibility to certain health conditions, including those affecting our eyes. The World Health Organisation (WHO) estimates approximately 2.7 billion people worldwide are impacted by poor vision that isn’t corrected. Further, an estimated 2.2 billion people suffer from visual impairment or blindness. This underlines the importance of understanding the role of genetics in our eye health, as it could significantly influence both preventative and curative measures.

Genetics and Vision: A Closer Look
Our genes serve as the blueprint for our eyes, dictating every aspect from their colour to their function. Understanding this genetic influence can help us better comprehend our vision.

1. Eye Colour:
Two genes, OCA2 and HERC2, play a significant role in determining the colour of our eyes. While brown eyes are the most common, a unique combination of inherited genes can lead to different eye colours.

2. Eye Size and Shape:
The shape and size of our eyes are also determined by our genes. The genes SH3PXD2B, AXL, and PAX6 are particularly involved in this process.

3. Vision Capabilities:
Genes also influence the sharpness of our vision. Conditions like nearsightedness or farsightedness often run in families, passed down generations. Genes such as GJD2 and RASGRF1 have been linked to these vision issues.

4. Eye Health:
Genes can also make you more susceptible to certain eye conditions, like macular degeneration, glaucoma, and retinal degeneration.

Common Hereditary Eye Conditions
While lifestyle and environmental factors can influence our eye health, certain conditions are hereditary. Here are some common genetic eye conditions:

1. Myopia (Nearsightedness):
Myopia, or nearsightedness, is a condition that affects your ability to see objects at a distance. This condition often runs in families.

2. Hyperopia (Farsightedness):
Hyperopia, or farsightedness, is a condition where you cannot see things close to you. This condition can also be inherited.

3. Astigmatism:
Astigmatism causes blurry vision due to an uneven cornea and can be inherited.

4. Amblyopia:
Also known as lazy eye, Amblyopia is an eye development disorder that can be seen in early childhood.

5. Glaucoma:
Glaucoma is a condition where the pressure inside the eye rises, damaging the optic nerve and leading to a loss of peripheral vision.

6. Cataracts:
A cataract is a clouding of the lens inside the eye, which blocks light from entering and results in reduced vision.

7. Age-Related Macular Degeneration (AMD):
AMD impacts the macula, the area of the retina responsible for clear, central vision, and is a significant cause of vision loss in older adults.

8. Retinitis Pigmentosa:
Retinitis pigmentosa refers to a group of related disorders that lead to gradual vision loss due to retinal degeneration.

9. Color Blindness:
Color blindness is marked by difficulty in distinguishing between different colors.

Managing Genetic Eye Conditions
Having a family history of eye conditions does not guarantee you will develop them. However, if you do have a history, it’s important to take the necessary precautions to reduce your risk. Regular eye check-ups, maintaining a healthy lifestyle, protecting your eyes from harmful UV rays, and considering genetic counselling can all help.

Modern Eye Treatments: LASIK and Beyond
Modern eye care solutions like LASIK eye surgery can correct various vision impairments, including myopia, hyperopia, glaucoma, and cataracts. At Shankar Netrika Eye Centre, we offer comprehensive consultations and personalized care to ensure that every individual receives the best treatment suited to their specific needs. Our LASIK procedures utilize advanced technology and skilled professionals to provide safe and effective results. Visit our website for more information or to schedule an appointment.

Dr. Navin Kumar Gupta
http://shankarnetrika.com

Director, Shankar Netrika Medical Retina Specialist Retina Fellow, University of California, Irvine, USA (2008-2010) Research Fellow, Johns Hopkins Hospital, Baltimore, USA (2007-2008) Anterior Segment Fellow, Aravind Eye Hospital, Madurai (2004-2006) Affiliate of SEE International, Santa Barbara, USA Collaborator and Advisor of Phaco Training Program, Anjali Eye Center

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