The most common systemic manifestation of Toxoplasmosis
is lymphadenopathy especially involving cervical lymph
nodes.
Ocular toxoplasmosis is primarily a disease of the retina.
It shows a high rate of posterior pole involvement specially the macula.
The organisms gain access to the eye via either the optic nerve or posterior ciliary arteries.
The clinical sign is typically retinitis manifesting as yellow exudate with
ill-defined borders.
The lesion classically begins in the superficial layers of the retina, progressing
gradually to the deeper layers and then even involving the choroid or the
sclera.
Vitritis is often present and can be the the reason both for the decreased
vision for the patient and poor visualization of the retina for the
ophthalmologists.
The textbooks often describe it is as “headlight seen in the fog”.